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ICC Test Kits Immunocytochemistry P16 Protein Staining Test Kit Biomarker Tumor Suppressor
Product Name
Keypath p16 Immunoassay Test Kit (ICC)
Introduction
p16 is a protein that slows cell division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby acting as a tumor suppressor. It is encoded by the CDKN2A gene. A deletion (the omission of a part of the DNA sequence during replication) in this gene can result in insufficient or non-functional p16, accelerating the cell cycle and resulting in many types of cancer.
p16 is a biomarker to improve the histological diagnostic accuracy of grade 3 cervical intraepithelial neoplasia (CIN). p16 is also implicated in the prevention of melanoma, oropharyngeal squamous cell carcinoma, cervical cancer, vulvar cancer and esophageal cancer.
Product Information
| Name | Keypath p16 Immunoassay Test Kit(ICC) |
| Applied to | Detection of cervical cancer by cervical epithelial cells |
| Composition | p16 antibody reagent, PBST (20×), Antigen repair solution (50×), Blocker, Penetrant, HRP labeked secondary antibody, Chromogenic solution A, Chromogenic solution B, Hematoxylin restaining solution, Bluing solution, Instruction for Use |
|
Signal at |
Nucleus/plasma |
| Positive judgement | Nucleus/plasma colored in tan or tan coloration |
| Specification | 25Tests/Kit; 50Tests/Kit; 100Tests/Kit |
| Size of packing box | 140*97*73 mm |